Assistant Secretary for Preparedness and Response

Ensuring American Pharmaceutical Supply Chain Resilience by Filling the Strategic Active Pharmaceutical Ingredients Reserve

This Executive Order directs the Department of Health and Human Services to fill the Strategic Active Pharmaceutical Ingredients Reserve (SAPIR) with a 6-month supply of APIs for approximately 26 critical drugs, prioritizing domestic manufacturing. It also requires updating the essential medicines list and planning a second repository, while criticizing the prior administration for failing to advance domestic pharmaceutical production.